| DATE | OPPONENT | GAME TIME | SCORE | LOCATION |
| Wednesday, March 17, 2021 | Canon-Mac (scrimm.) | 6:00 PM | N/A | Myers Law Group Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Monday, March 22, 2021 | Mt. Lebanon (scrimm.) | 6:00 PM | N/A | Myers Law Group Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Wednesday, March 31, 2021 | Butler* | 7:45 PM | | NexTier Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Tuesday, April 6, 2021 | Bethel Park | 7:45 PM | | Myers Law Group Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Thursday, April 8, 2021 | @Allderdice* | 7:00 PM | | Cupples Stadium, 800 E Carson Street, Pittsburgh, PA 15203 |
| Wednesday, April 14, 2021 | Shady Side* | 7:00 PM | | NexTier Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Friday, April 16, 2021 | Upper St. Clair # | 7:45 PM | | Myers Law Group Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Monday, April 19, 2021 | @Peters | 7:30 PM | | Peters Township HS Stadium, 264 E McMurray Road, McMurray, PA 15317 |
| Friday, April 23, 2021 | @Pine * | 7:30PM | | Pine Richland HS Stadium, 700 Warrendale Road, Gibsonia, PA 15044 |
| Wednesday, April 28, 2021 | @ Norwin * | 7:30 PM | | Norwin HS Stadium, 251 McMahon Drive, Irwin, PA 15642 |
| Friday, April 30, 2021 | North Allegheny * | 7:45 PM | | NexTier Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Wednesday, May 5, 2021 | Fox Chapel * | 7:45 PM | | NexTier Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Friday, May 7, 2021 | North Catholic | 7:45 PM | | Meyers Law Group Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Monday, May 10, 2021 | Hampton ^ | 7:45 PM | | NexTier Stadium, SV Senior High School, 128 Seneca School Road, Harmony, PA 16037 |
| Wednesday, May 12, 2021 | Central * | 7:30 PM | | Central Catholic HS, 4720 Fifth Ave., Pittsburgh, PA 15213 |
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